PK-MERZ® is a drug in tablet form, included in the group of antiparkinsonian drugs. PK-MERZ® contains amantadine sulphate.
PK-MERZ® is used in the following conditions:
• Parkinson treatment and treatment of drug-induced muscle responses (muscle stifness, involuntary tremors (dyskinesia), decrease as well as cessation of motor function or activity)
• Treatment of symptoms that occur after brain surgery (stereotactic surgery) without opening the skull (motor function disorders such as tremor)
Parkinson disease: If PK-MERZ® monotherapy treatment is to be started for the first time, treatment with 2 tablets per day should be started. The full activity begins to appear within 48 hours.Treatment should be started with 1 tablet per day (100 mg / day) in patients who have another medical illness or who take high dose of other antiparkinsonian drugs. After one or couple of weeks of treatment, the dose can be increased to 2 tablets (200 mg/day), which is taken at the standard level of 1 tablet twice daily.In patients who do not respond to a daily dose of 2 tablets (200 mg), the dose can be increased up to 4 tablets (400 mg) to be taken daily in a divided fashion. The dose should not exceed 6 tablets per day (600 mg).